Introduction

You have reached the public blog pages of Pietà Georgina Schofield. I make no apologies that it is uncompromisingly solarised-dark.

It is a record of some of the things I get up to other than coding in R which is recorded at my GitHub Site.

Site Content

Publications

This is a list of some of the peer reviewed publications that I have contributed to through my paid employment over the years

Abuzour, Aseel S., Samantha A. Wilson, Alan A. Woodall, Frances S. Mair, Andrew Clegg, Eduard Shantsila, Mark Gabbay, et al. 2024. “A Qualitative Exploration of Barriers to Efficient and Effective Structured Medication Reviews in Primary Care: Findings from the DynAIRx Study.” PLOS ONE 19 (8): e0299770. https://doi.org/10.1371/journal.pone.0299770.
Anandanadesan, A., M. A. J. Chaplain, A. J. Karley, S. F. Hubbard, and P. G. Schofield. 2011. “Mathematical Modeling of the Spatio-Temporal Dynamics of Aphid-Parasitoid-Plant-Virus Interactions.” Aspects of Applied Biology, no. No.109: 107–13. https://www.cabdirect.org/cabdirect/abstract/20133172708.
Ball, D., P. Schofield, F. Eddy, G. Codd, and S. F. Hubbard. 2005. “Characterisation of the Locomotor Activity Response of Larval Zebrafish (Danio Rerio) to Ethanol Using a Novel Non-Invasive Digital Tracking System.” In Comparative Biochemistry and Physiology A Molecular & Integrative Physiology, 141:S195. Elsevier Science Inc.
Batie, Michael, Julianty Frost, Mark Frost, James W. Wilson, Pieta Schofield, and Sonia Rocha. 2019. “Hypoxia Induces Rapid Changes to Histone Methylation and Reprograms Chromatin.” Science 363 (6432): 1222–26. https://doi.org/10.1126/science.aau5870.
Bodger, Keith, Thomas Mair, Peità Schofield, Benjamin Silberberg, Steve Hood, and Kate M. Fleming. 2023. “Outcomes of First Emergency Admissions for Alcohol-Related Liver Disease in England over a 10-Year Period: Retrospective Observational Cohort Study Using Linked Electronic Databases.” BMJ Open 13 (11): e076955. https://doi.org/10.1136/bmjopen-2023-076955.
Burgess, A. E. F., P. G. Schofield, S. F. Hubbard, M. a. J. Chaplain, and T. Lorenzi. 2016. “Dynamical Patterns of Coexisting Strategies in a Hybrid Discrete-continuum Spatial Evolutionary Game Model.” Mathematical Modelling of Natural Phenomena 11 (5): 49–64. https://doi.org/10.1051/mmnp/201611504.
Burgess, Andrew E. F., Tommaso Lorenzi, Pietà G. Schofield, Stephen F. Hubbard, and Mark A. J. Chaplain. 2017. “Examining the Role of Individual Movement in Promoting Coexistence in a Spatially Explicit Prisoner’s Dilemma.” Journal of Theoretical Biology 419: 323–32. https://doi.org/10.1016/j.jtbi.2017.02.028.
Davies, W J, M A Bacon, R G Sharp, H G Jones, P G Schofield, C J Atkinson, O M Grant, and M York. 2008. “Enhancing the Quality of Hardy Nursery Stock and Sustainability of the Industry Through Novel Water-Saving Techniques.” Horticultural Development Company.
Fytrou, Anastasia, Peter G Schofield, Alex R Kraaijeveld, and Stephen F Hubbard. 2006. “Wolbachia Infection Suppresses Both Host Defence and Parasitoid Counter-Defence.” Proceedings of the Royal Society B: Biological Sciences 273 (1588): 791–96.
Gierliński, Marek, Christian Cole, Pietà Schofield, Nicholas J. Schurch, Alexander Sherstnev, Vijender Singh, Nicola Wrobel, et al. 2015. “Statistical Models for RNA-seq Data Derived from a Two-Condition 48-Replicate Experiment.” Bioinformatics 31 (22): 3625–30. https://doi.org/10.1093/bioinformatics/btv425.
Gkikopoulos, Triantaffyllos, Pieta Schofield, Vijender Singh, Marina Pinskaya, Jane Mellor, Michaela Smolle, Jerry L Workman, Geoffrey J Barton, and Tom Owen-Hughes. 2011. “A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization.” Science 333: 1758–60.
Gkikopoulos, Triantaffyllos, Vijender Singh, Kyle Tsui, Salma Awad, Matthew J Renshaw, Pieta Scholfield, Geoffrey J Barton, Corey Nislow, Tomoyuki U Tanaka, and Tom Owen-Hughes. 2011. “The SWI/SNF Complex Acts to Constrain Distribution of the Centromeric Histone Variant Cse4.” Embo Journal 30: 1919–27.
Head, Anna, Kate Fleming, Chris Kypridemos, Pieta Schofield, Jonathan Pearson-Stuttard, and Martin O’Flaherty. 2021. “Inequalities in Incident and Prevalent Multimorbidity in England, 2004–19: A Population-Based, Descriptive Study.” The Lancet Healthy Longevity 2 (8): e489–97. https://doi.org/10.1016/S2666-7568(21)00146-X.
Henney, Alex E, Conor S Gillespiec, Jonathan Y M Lai, Pieta Schofield, David R Riley, Rishi Caleyachetty, Thomas M Barber, et al. 2024. “Risk of Type 2 Diabetes, MASLD and Cardiovascular Disease in People Living With Polycystic Ovary Syndrome.” The Journal of Clinical Endocrinology & Metabolism, July, dgae481. https://doi.org/10.1210/clinem/dgae481.
Jones, Hamlyn, and Pieta Schofield. 2008. “Thermal and Other Remote Sensing of Plant Stress.” General Applications Plant Physiology 34: 19–32.
Mbizvo, Gashirai K., Glen P. Martin, Matthew Sperrin, Laura J. Bonnett, Pieta Schofield, Iain Buchan, Gregory YH Lip, and Anthony G. Marson. 2024. “An International Study to Investigate and Optimise the Safety of Discontinuing Valproate in Young Men and Women with Epilepsy: Protocol.” PloS One 19 (8): e0306226. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0306226.
Meier, Bettina, Nadezda V. Volkova, Ye Hong, Pieta Schofield, Peter J. Campbell, Moritz Gerstung, and Anton Gartner. 2018. “Mutational Signatures of DNA Mismatch Repair Deficiency in C. Elegans and Human Cancers.” Genome Research 28 (5): 666–75. https://doi.org/10.1101/gr.226845.117.
Mohan, Sumitra, Victoria Foy, Mahmood Ayub, Hui Sun Leong, Pieta Schofield, Sudhakar Sahoo, Tine Descamps, et al. 2020. “Profiling of Circulating Free DNA Using Targeted and Genome-wide Sequencing in Patients with SCLC.” Journal of Thoracic Oncology 15 (2): 216–30. https://doi.org/10.1016/j.jtho.2019.10.007.
Mohan, Sumitra, Victoria Foy, Hui Sun Leong, Pietà G. Schofield, Mahmood Ayub, Nigel K. Smith, Sudhakar Sahoo, et al. 2018. “Abstract 5602: Detection of Circulating Cell-Free Tumor DNA (ctDNA) in Patients with Small Cell Lung Cancer (SCLC).” Cancer Research 78 (13 Supplement): 5602–2. https://doi.org/10.1158/1538-7445.AM2018-5602.
Pearce, Ian G, Mark A J Chaplain, Peter G Schofield, Alexander R A Anderson, and Stephen F Hubbard. 2006. “Modelling the Spatio-Temporal Dynamics of Multi-Species Host-Parasitoid Interactions: Heterogeneous Patterns and Ecological Implications.” J Theor Biol 241 (4): 876–86.
Pearce, Ian G, Mark A J Chaplain, Pieta G Schofield, Alexander R A Anderson, and Stephen F Hubbard. 2007. “Chemotaxis-Induced Spatio-Temporal Heterogeneity in Multi-Species Host-Parasitoid Systems.” Journal of Mathematical Biology 55: 365–88.
Preedy, Katharine F, Pieta G Schofield, Mark A J Chaplain, and Stephen F Hubbard. 2007. “Disease Induced Dynamics in Host-Parasitoid Systems: Chaos and Coexistence.” Journal of the Royal Society Interface 4: 463–71.
Preedy, Katharine F, Pieta G Schofield, Sijia Liu, Anastasios Matzavinos, Mark A J Chaplain, and Stephen F Hubbard. 2010. “Modelling Contact Spread of Infection in Host-Parasitoid Systems: Vertical Transmission of Pathogens Can Cause Chaos.” Journal of Theoretical Biology 262: 441–51.
Reed, Bernard, Stephenne Rhodes, Pieta Schofield, and Kevan Wylie. 2009. “Gender Variance in the UK: Prevalence, Incidence Growth and Geographic Distribution.” GIRES Technical Report.
Roberts, David M, Pieta G Schofield, Suzanne Donn, and Tim J Daniell. 2012. “Directed Terminal Restriction Analysis Tool (DRAT): An Aid to Enzyme Selection for Directed Terminal-Restriction Fragment Length Polymorphisms.” Methods in Ecology and Evolution 3: 24–28.
Schofield, P. 2002. “Spatially Explicit Models of Turelli-Hoffmann Wolbachia Invasive Wave Fronts.” Journal of Theoretical Biology 215 (1): 121–31.
Schofield, P, M. A. J. Chaplain, and S F Hubbard. 2000. “Spatio-Temporal Mathematical Models of Host-Parasitoid Systems.” European Communications of Mathematical and Theoretical Biology 2 (12-17).
Schofield, Peter G. 2002. “Spatio-Temporal Mathematical Models for the Investigation of Host-Parasitoid Systems and Wolbachia-Infection Dynamics.” PhD thesis, Dundee: University of Dundee.
Schofield, Peter G, Mark A J Chaplain, and Stephen F Hubbard. 2002. “Mathematical Modelling of Host-Parasitoid Systems: Effects of Chemically Mediated Parasitoid Foraging Strategies on Within- and Between-Generation Spatio-Temporal Dynamics.” J. Theor. Biol. 214: 31–47.
———. 2005. “Dynamic Heterogeneous Spatio-Temporal Pattern Formation in Host-Parasitoid Systems with Synchronised Generations.” J Math Biol 50 (5): 559–83.
Schofield, Peter, Mark Chaplain, and Stephen Hubbard. 2005. “Evolution of Searching and Life History Characteristics in Individual-Based Models of Host-Parasitoid-Microbe Associations.” J Theor Biol 237 (1): 1–16.
Schofield, Susie J, and Pieta G Schofield. 2016. “What’s in a Name? Word Inflation, Punctuation, Abbreviation and Cloud Formation.” Medical Education 50 (12): 1264–68. https://doi.org/10.1111/medu.13099.
Schurch, Nicholas J., Pietá Schofield, Marek Gierliński, Christian Cole, Alexander Sherstnev, Vijender Singh, Nicola Wrobel, et al. 2016. “How Many Biological Replicates Are Needed in an RNA-seq Experiment and Which Differential Expression Tool Should You Use?” RNA 22 (6): 839–51. https://doi.org/10.1261/rna.053959.115.
Seifert, Anne, Pietà Schofield, Geoffrey J Barton, and Ronald T Hay. 2015. “Proteotoxic Stress Reprograms the Chromatin Landscape of SUMO Modification.” Science Signalling 8 (384).
Steiner, Ivana, Teresita Del N. J. Flores-Tellez, Renaud Mevel, Amin Ali, Pengbo Wang, Pieta Schofield, Caron Behan, et al. 2023. “Autocrine Activation of MAPK Signaling Mediates Intrinsic Tolerance to Androgen Deprivation in LY6D Prostate Cancer Cells.” Cell Reports 42 (4): 112377. https://doi.org/10.1016/j.celrep.2023.112377.
Wiechens, Nicola, Vijender Singh, Triantaffyllos Gkikopoulos, Pieta Schofield, Sonia Rocha, and Tom Owen-Hughes. 2016. “The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes Adjacent to CTCF and Other Transcription Factors.” PLoS Genetics 12 (3): e1005940. https://doi.org/10.1371/journal.pgen.1005940.